DISCERNING PRIMARY AND SECONDARY FACTORS RESPONSIBLE FOR CLINICAL FATIGUE IN MULTISYSTEM DISEASES


Inhibition of Metastatic Hepatocarcinoma by Combined Chemotherapy with Silencing VEGF/VEGFR2 Genes through a GalNAc-Modified Integrated Therapeutic System

Hepatocellular carcinoma (HCC) is a highly malignant tumor related to high mortality and is still lacking a satisfactory cure.Tumor metastasis is currently a major challenge of cancer treatment, which is highly related to angiogenesis.The vascular endothelial growth factor (VEGF)/VEGFR signaling pathway is thus becoming an attractive therapeutic ta

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Impact of Mutations in the Hemagglutinin of H10N7 Viruses Isolated from Seals on Virus Replication in Avian and Human Cells

Wild birds are the reservoir for low-pathogenic avian influenza viruses, which are frequently transmitted to domestic birds and occasionally to mammals.In 2014, an H10N7 virus caused severe mortality in harbor seals in northeastern satisfyer pro penguin next generation Europe.Although the hemagglutinin (HA) of this virus was closely related to H10

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